The Masterbox Q500L is a compact chassis that still allows for a full-size ATX board to be installed. That, however, is not what makes it unique. It is the way that the case may be used as both a tower or desktop with the freedom to install fans or liquid cooling nearly anywhere and the ability to move the I/O panels around as well.
Any major computer upgrade generally requires a full software reinstall too. No so if you heed the advice in the guide to Upgrading a Motherboard without Reinstalling. PCSTATS Tips